The Explorer cannot auto-scan, although I suppose with a savvy enough macro'ing application it might be possible to try and set this up. That said, intraday scans are possible but can be slow to complete. The Explorer does have a fairly sensitive timeout period before moving on to the next symbol. If it takes too long to collect the intraday history needed to start the scan, it will give up and move on to the next security.
You can mitigate this somewhat by using "Load Minimum Records" in the Explorer-->Options, but for many exponential calculations you will want to make sure and load as much history into the explorer as you load into your charts, and "Load Minimum Records" may not be possible for your formulas (especially indicators that use exponential calculations, like RSI).
The number of securities you decide to scan (with Data on Demand) will also determine the success. Using Local Intraday Data would work significantly better for the Explorer, but Local Intraday Securities can be very difficult to maintain. Realistically you would not be able to collect/updating 1000 local intraday securities. Most data providers have a symbol limit for the amount of securities you can be updating at one time.
This would basically leave you with Data On Demand as the only realistic option, and scanning 1,000 securities on-demand every minute would likely not be possible (it would likely not even be close to completing a scan of 1,000 symbols every minute on demand).
I suppose the short answer is no, trying to scan 1,000 intraday securities every minute is simply not going to be feasible at this time.